Silencing KIF18B enhances radiosensitivity: identification of a promising therapeutic target in sarcoma

Background: Sarcomas are rare heterogeneous tumours, derived from primitive mesenchymal stem cells, with more than 100 distinct subtypes. Radioresistance remains a major clinical challenge for sarcomas, demanding urgent for effective biomarkers of radiosensitivity. Methods: The radiosensitive gene K...

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Bibliographic Details
Main Authors: Wensi Liu, Zhaojin Yu, Haichao Tang, Xiangyi Wang, Bing Zhang, Jianhang Zhao, Xinli Liu, Jingdong Zhang, Minjie Wei
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420304321