Cysteine dioxygenase 1 attenuates the proliferation via inducing oxidative stress and integrated stress response in gastric cancer cells

Abstract Whereas cysteine dioxygenase 1 (CDO1) expression is lost due to its hypermethylated promoter across a range of cancer types including gastric cancer (GC), its functions and molecular underpinnings remain largely unknown. Here we demonstrate that reduced CDO1 expression is indicative of unfa...

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Bibliographic Details
Main Authors: Gang Ma, Zhenzhen Zhao, Yang Qu, Fenglin Cai, Siya Liu, Han Liang, Rupeng Zhang, Jingyu Deng
Format: Article
Language:English
Published: Nature Publishing Group 2022-12-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01277-x