Expression and Clinical Significance of MDM2 in Non-Functioning PitNETs

<i>Background and Objective</i>: Non-functioning pituitary neuroendocrine tumors (NF-PitNETs) represent a heterogeneous tumor type that lacks effective medical treatment. MDM2, the main negative regulator of p53, binds to and forms a stable complex with p53 to regulate its activity. In t...

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Bibliographic Details
Main Authors: Xiaohui Yao, Qian Liu, Sida Zhao, Rui Cheng, Chunhui Liu, Gangli Zhang
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/59/2/373