Expression and Clinical Significance of MDM2 in Non-Functioning PitNETs
<i>Background and Objective</i>: Non-functioning pituitary neuroendocrine tumors (NF-PitNETs) represent a heterogeneous tumor type that lacks effective medical treatment. MDM2, the main negative regulator of p53, binds to and forms a stable complex with p53 to regulate its activity. In t...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-02-01
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Series: | Medicina |
Subjects: | |
Online Access: | https://www.mdpi.com/1648-9144/59/2/373 |