Conditioned Media from Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Inhibits Melanogenesis by Promoting Proteasomal Degradation of MITF.

Conditioned Media from Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Inhibits Melanogenesis by Promoting Proteasomal Degradation of MITF.

Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) secrete various beneficial molecules, which have anti-apoptotic activity and cell proliferation. However, the effect of hUCB-MSCs in melanogenesis is largely unclear. In this study, we show that conditioned media (CM) derived from...

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Bibliographic Details
Main Authors: Eun Sung Kim, Hong Bae Jeon, Hoon Lim, Ji Hyun Shin, So Jung Park, Yoon Kyung Jo, Wonil Oh, Yoon Sun Yang, Dong-Hyung Cho, Ju-Yeon Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4449211?pdf=render

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http://europepmc.org/articles/PMC4449211?pdf=render

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