Intra-articular injection of placental mesenchymal stromal cells ameliorates pain and cartilage anabolism/catabolism in knee osteoarthritis

Intra-articular injection of placental mesenchymal stromal cells ameliorates pain and cartilage anabolism/catabolism in knee osteoarthritis

Background: Knee Osteoarthritis (kOA), the most common joint degenerative disorder, lacks effective therapeutics. Placenta-derived mesenchymal stromal cells (PMSCs) are effective in tissue repairing and generation, which have potential in treating kOA. This study aimed to determine the anti-kOA effi...

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Bibliographic Details
Main Authors: Mengqiang Fan, Jingwen Zhang, Li Zhou, Zuxiang Chen, Ronghua Bao, Longpo Zheng, Peijian Tong, Yuhai Ma, Letian Shan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Pharmacology
Subjects:
osteoarthritis
paracrine
conditioned medium
rat
placenta-derived mesenchymal stromal cells
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.983850/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.983850/full

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