Peripheral NF-κB dysregulation in people with schizophrenia drives inflammation: putative anti-inflammatory functions of NF-κB kinases

Abstract Elevations in plasma levels of pro-inflammatory cytokines and C-reactive protein (CRP) in patient blood have been associated with impairments in cognitive abilities and more severe psychiatric symptoms in people with schizophrenia. The transcription factor nuclear factor kappa B (NF-κB) reg...

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Bibliographic Details
Main Authors: Caitlin E. Murphy, Adam K. Walker, Maryanne O’Donnell, Cherrie Galletly, Andrew R. Lloyd, Dennis Liu, Cynthia Shannon Weickert, Thomas W. Weickert
Format: Article
Language:English
Published: Nature Publishing Group 2022-01-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01764-2