Broad-spectrum capture of clinical pathogens using engineered Fc-mannose-binding lectin enhanced by antibiotic treatment [version 1; peer review: 2 approved]

Broad-spectrum capture of clinical pathogens using engineered Fc-mannose-binding lectin enhanced by antibiotic treatment [version 1; peer review: 2 approved]

Background: Fc-mannose-binding lectin (FcMBL), an engineered version of the blood opsonin MBL that contains the carbohydrate recognition domain (CRD) and flexible neck regions of MBL fused to the Fc portion of human IgG1, has been shown to bind various microbes and pathogen-associated molecular patt...

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Bibliographic Details
Main Authors: Benjamin T. Seiler, Mark Cartwright, Alexandre L. M. Dinis, Shannon Duffy, Patrick Lombardo, David Cartwright, Elana H. Super, Jacqueline Lanzaro, Kristen Dugas, Michael Super, Donald E. Ingber
Format: Article
Language:English
Published: F1000 Research Ltd 2019-01-01
Series:F1000Research
Online Access:https://f1000research.com/articles/8-108/v1

Internet

https://f1000research.com/articles/8-108/v1

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