Arsenic Trioxide Selectively Induces Apoptosis within the Leukemic Cells of APL Patients with t(15;17) Translocation Possibly through the Fas Pathway

Arsenic Trioxide Selectively Induces Apoptosis within the Leukemic Cells of APL Patients with t(15;17) Translocation Possibly through the Fas Pathway

Background: Acute Promyelocytic Leukemia is a sub-type of acute myelogenous leukemia that occurs in about 10-15% of patients with AML. Approximately 20%-30% of these patients, who are treated with the current standard All Trans Retinoic Acid (ATRA) and Anthracyclin-based chemotherapy regimen, suffer...

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Bibliographic Details
Main Authors: A.R Ardjmand, K Alimoghaddam, F Zaker, A Ghavamzadeh, M Jahani
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2004-03-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Acute Promyelocytic Leukemia
Arsenic trioxide
Apoptosi
Fas/Apo1
Flowcytometry
Online Access:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/172

Internet

https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/172

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