miR‐181a/b downregulation: a mutation‐independent therapeutic approach for inherited retinal diseases

miR‐181a/b downregulation: a mutation‐independent therapeutic approach for inherited retinal diseases

Abstract Inherited retinal diseases (IRDs) are a group of diseases whose common landmark is progressive photoreceptor loss. The development of gene‐specific therapies for IRDs is hampered by their wide genetic heterogeneity. Mitochondrial dysfunction is proving to constitute one of the key pathogeni...

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Bibliographic Details
Main Authors: Sabrina Carrella, Martina Di Guida, Simona Brillante, Davide Piccolo, Ludovica Ciampi, Irene Guadagnino, Jorge Garcia Piqueras, Mariateresa Pizzo, Elena Marrocco, Marta Molinari, Georgios Petrogiannakis, Sara Barbato, Yulia Ezhova, Alberto Auricchio, Brunella Franco, Elvira De Leonibus, Enrico Maria Surace, Alessia Indrieri, Sandro Banfi
Format: Article
Language:English
Published: Springer Nature 2022-11-01
Series:EMBO Molecular Medicine
Subjects:
inherited retinal diseases
miR‐181
mitochondria
photoreceptor
therapy
Online Access:https://doi.org/10.15252/emmm.202215941

Internet

https://doi.org/10.15252/emmm.202215941

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