Cre/loxP-Based Reversible Immortalization of Human Hepatocytes

An ideal alternative to the primary human hepatocytes for hepatocyte transplantation would be to use a clonal cell line that grows economically in culture and exhibits the characteristics of differentiated, nontransformed hepatocytes following transplantation. The purpose of the present studies was...

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Bibliographic Details
Main Authors: Naoya Kobayashi M.D., Ph.D., Hirofumi Noguchi, Karen A. Westerman, Takamasa Watanabe, Toshihisa Matsumura, Toshinori Totsugawa, Toshiyoshi Fujiwara, Philippe Leboulch, Noriaki Tanaka
Format: Article
Language:English
Published: SAGE Publishing 2001-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000001783986558