Clinical, hormonal and pathomorphological markers of somatotroph pituitary neuroendocrine tumors predicting the treatment outcome in acromegaly

BackgroundTranssphenoidal adenomectomy (TSS) of somatotroph pituitary neuroendocrine tumor (PitNET) is the first-line treatment of acromegaly. Pharmacological treatment is recommended if surgery is contraindicated or did not lead to disease remission. The choice of treatment best fitting each patien...

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Main Authors: Agnieszka Tomasik, Maria Stelmachowska-Banaś, Maria Maksymowicz, Izabella Czajka-Oraniec, Dorota Raczkiewicz, Grzegorz Zieliński, Jacek Kunicki, Wojciech Zgliczyński
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Endocrinology
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Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.957301/full