TMAO promotes apoptosis and oxidative stress of pancreatic acinar cells by mediating IRE1α-XBP-1 pathway

Background: Acute pancreatitis caused by hyperlipidemia is a severe life-threatening condition. Therefore, it is urgent to develop new therapeutic methods to treat this disease. Methods: Cell viability was determined by the Cell Counting Kit-8 (CCK-8) assay. Western blotting (WB) was used to detect...

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Bibliographic Details
Main Authors: Guodong Yang, Xiaoying Zhang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:The Saudi Journal of Gastroenterology
Subjects:
Online Access:http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2021;volume=27;issue=6;spage=361;epage=369;aulast=Yang