Engineering single-cycle MeV vector for CRISPR-Cas9 gene editing

Engineering single-cycle MeV vector for CRISPR-Cas9 gene editing

CRISPR-Cas9-mediated gene editing has vast applications in basic and clinical research and is a promising tool for several disorders. Our lab previously developed a non-integrating RNA virus, measles virus (MeV), as a single-cycle reprogramming vector by replacing the viral attachment protein with t...

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Bibliographic Details
Main Authors: Ramya Rallabandi, Brenna Sharp, Spencer Majerus, Austin Royster, Sarrianna Hoffer, Mia Ikeda, Patricia Devaux
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
measles
viral vector
CRISPR
Cas9
gene editing
NHEJ
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050124001062

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http://www.sciencedirect.com/science/article/pii/S2329050124001062

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