Coffee and the risk of osteoarthritis: a two-sample, two-step multivariable Mendelian randomization study

Coffee and the risk of osteoarthritis: a two-sample, two-step multivariable Mendelian randomization study

Purpose: To investigate the potential causal relationship between coffee consumption and osteoarthritis (OA), and to disentangle whether body mass index (BMI) and Bone mineral density (BMD) mediate this relationship.Methods: We performed two-sample and two-step Mendelian randomization (MR) analyses...

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Bibliographic Details
Main Authors: Wenzheng Zhang, Xuefeng Lei, Yihui Tu, Tong Ma, Tao Wen, Tao Yang, Long Xue, Jiazhong Ji, Huaming Xue
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Genetics
Subjects:
osteoarthritis
coffee type
coffee intake
Mendelian randomization
mediating effects
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1340044/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2024.1340044/full

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