Roles of metalloproteinase-3 and aggrecanase 1 and 2 in aggrecan cleavage during human meniscus degeneration

The meniscus plays important roles in proper knee function. It was recently reported that meniscus degeneration was associated with progression of osteoarthritis (OA). However, little is known about the effects of degradative enzymes on the meniscus matrix, primarily collagen type I and aggrecan, du...

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Bibliografische gegevens
Hoofdauteurs: Naoki Ishiguro, Yoshimichi Saito, Toshihisa Kojima, Gintaro Ishihara
Formaat: Artikel
Taal:English
Gepubliceerd in: Open Medical Publishing 2009-10-01
Reeks:Orthopedic Reviews
Onderwerpen:
Online toegang:http://www.pagepress.org/journals/index.php/or/article/view/598