Construction of ultrasound-responsive urokinase precise controlled-release nanoliposome applied for thrombolysis

Urokinase is widely used in the dissolution of an acute pulmonary embolism due to its high biocatalytic effect. However, how to precisely regulate its dose, avoid the side effects of hemolysis or ineffective thrombolysis caused by too high or too low a dose, and seize the golden time of acute pulmon...

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Bibliographic Details
Main Authors: Yongliang Fan, Li Liu, Fang Li, Hang Zhou, Yizhou Ye, Chunping Yuan, Hongli Shan, Wangfu Zang, Yu Luo, Sijing Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.923365/full