Prenatal infection and adolescent social adversity affect microglia, synaptic density, and behavior in male rats

Prenatal infection and adolescent social adversity affect microglia, synaptic density, and behavior in male rats

Maternal infection during pregnancy and childhood social trauma have been associated with neurodevelopmental and affective disorders, such as schizophrenia, autism spectrum disorders, bipolar disorder and depression. These disorders are characterized by changes in microglial cells, which play a nota...

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Bibliographic Details
Main Authors: Cyprien G.J. Guerrin, Kavya Prasad, Daniel A. Vazquez-Matias, Jing Zheng, Maria Franquesa-Mullerat, Lara Barazzuol, Janine Doorduin, Erik F.J. de Vries
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Neurobiology of Stress
Subjects:
Maternal immune activation
Social adversity
Microglia
Synaptic density
Synaptophysin
Neurodevelopmental disorders
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289523000681

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http://www.sciencedirect.com/science/article/pii/S2352289523000681

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