The endogenous Mtv8 locus and the immunoglobulin repertoire

The vast diversity of mammalian adaptive antigen receptors allows for robust and efficient immune responses against a wide number of pathogens. The antigen receptor repertoire is built during the recombination of B and T cell receptor (BCR, TCR) loci and hypermutation of BCR loci. V(D)J recombinatio...

Full description

Bibliographic Details
Main Authors: Helen A. Beilinson, Steven A. Erickson, Tatyana Golovkina
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1345467/full