Transcriptome analysis of mesenchymal stromal cells of the large and small intestinal smooth muscle layers reveals a unique gastrontestinal stromal signature

Transcriptome analysis of mesenchymal stromal cells of the large and small intestinal smooth muscle layers reveals a unique gastrontestinal stromal signature

Mesenchymal stromal cells in the muscle layer of the large intestine are essential for the regulation of intestinal motility. They form electrogenic syncytia with the smooth muscle and interstitial cells of Cajal (ICCs) to regulate smooth muscle contraction. Mesenchymal stromal cells are present in...

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Bibliographic Details
Main Authors: Takashi Chaen, Tamaki Kurosawa, Kazuhisa Kishi, Noriyuki Kaji, Madoka Ikemoto-Uezumi, Akiyoshi Uezumi, Masatoshi Hori
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
Mesenchymal stromal cells
Platelet-derived growth factor receptor-alpha (PDGFRα)
Intestinal muscle layer
Flow cytometry
RNA-seq
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580823000596

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http://www.sciencedirect.com/science/article/pii/S2405580823000596

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