Identifying modules of cooperating cancer drivers

Abstract Identifying cooperating modules of driver alterations can provide insights into cancer etiology and advance the development of effective personalized treatments. We present Cancer Rule Set Optimization (CRSO) for inferring the combinations of alterations that cooperate to drive tumor format...

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Bibliographic Details
Main Authors: Michael I Klein, Vincent L Cannataro, Jeffrey P Townsend, Scott Newman, David F Stern, Hongyu Zhao
Format: Article
Language:English
Published: Springer Nature 2021-03-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.20209810