Phosphoramidate Azole Oligonucleotides for Single Nucleotide Polymorphism Detection by PCR

Phosphoramidate Azole Oligonucleotides for Single Nucleotide Polymorphism Detection by PCR

Detection of the Kirsten rat sarcoma gene (<i>KRAS</i>) mutational status is an important factor for the treatment of various malignancies. The most common <i>KRAS</i>-activating mutations are caused by single-nucleotide mutations, which are usually determined by using PCR, u...

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Bibliographic Details
Main Authors: Alexey S. Chubarov, Elizaveta E. Baranovskaya, Igor P. Oscorbin, Ivan I. Yushin, Maxim L. Filipenko, Dmitrii V. Pyshnyi, Svetlana V. Vasilyeva, Alexander A. Lomzov
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
PCR
allele-specific PCR
modified oligonucleotides
phosphoramide benzoazole oligonucleotides
PABAO
mutation detection
Online Access:https://www.mdpi.com/1422-0067/25/1/617

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https://www.mdpi.com/1422-0067/25/1/617

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