Stereotypic T cell receptor clonotypes in the thymus and peripheral blood of Myasthenia gravis patients

Stereotypic T cell receptor clonotypes in the thymus and peripheral blood of Myasthenia gravis patients

Myasthenia Gravis (MG) patients with anti-acetylcholine receptor (AChR) antibodies frequently show hyperplastic thymi with ectopic germinal centers, where autoreactive B cells proliferate with the aid of T cells. In this study, thymus and peripheral blood (PB) samples were collected from ten AChR an...

Full description

Bibliographic Details
Main Authors: Yonghee Lee, Seung Woo Kim, Eunjae Lee, Ha Young Shin, MinGi Kim, Chang Young Lee, Byung Jo Park, Ha Eun Kim, Young Ho Yang, Jinny Choi, Soyeon Ju, Jungheum Park, Namphil Kim, Jaewon Choi, Jin Gu Lee, Sunghoon Kwon, Junho Chung
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Heliyon
Subjects:
Myasthenia gravis
Acetylcholine receptor
T cell receptor repertoire
Thymus
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402402694X

Internet

http://www.sciencedirect.com/science/article/pii/S240584402402694X

Similar Items