Cardiac diastolic maladaptation is associated with the severity of exercise intolerance in sickle cell anemia patients

Cardiac diastolic maladaptation is associated with the severity of exercise intolerance in sickle cell anemia patients

Abstract This pilot study focusing on Sickle Cell Anemia (SCA) patients offers a comprehensive and integrative evaluation of respiratory, cardiovascular, hemodynamic, and metabolic variables during exercise. Knowing that diastolic dysfunction is frequent in this population, we hypothesize that a lac...

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Bibliographic Details
Main Authors: Thomas d’Humières, Antoine Bouvarel, Laurent Boyer, Laurent Savale, Henri Guillet, Lara Alassaad, Gonzalo de Luna, Enora Berti, Sihem Iles, Anne Laure Pham Hung d’Alexandry d’Orengiani, Etienne Audureau, Marie-Joelle Troupe, Reine-Claude Schlatter, Anaïs Lamadieu, Frédéric Galactéros, Geneviève Derumeaux, Laurent A. Messonnier, Pablo Bartolucci
Format: Article
Language:English
Published: Nature Portfolio 2024-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-61689-w

Internet

https://doi.org/10.1038/s41598-024-61689-w

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