Glycolytic metabolism is essential for CCR7 oligomerization and dendritic cell migration

Glycolytic metabolism is essential for CCR7 oligomerization and dendritic cell migration

The activation of dendritic cells (DC) is associated with a metabolic switch from oxidative to glycolytic metabolism. Here, the authors show that both strong and weak stimuli cause an immediate increase in glycolysis, but only strong stimuli induce long-term glycolytic reprogramming.

Bibliographic Details
Main Authors: Hannah Guak, Sara Al Habyan, Eric H. Ma, Haya Aldossary, Maia Al-Masri, So Yoon Won, Thomas Ying, Elizabeth D. Fixman, Russell G. Jones, Luke M. McCaffrey, Connie. M. Krawczyk
Format: Article
Language:English
Published: Nature Portfolio 2018-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-04804-6

Internet

https://doi.org/10.1038/s41467-018-04804-6

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