Quantitative glycoproteomics analysis identifies novel FUT8 targets and signaling networks critical for breast cancer cell invasiveness

Abstract Background We recently showed that fucosyltransferase 8 (FUT8)-mediated core fucosylation of transforming growth factor-β receptor enhances its signaling and promotes breast cancer invasion and metastasis. However, the complete FUT8 target glycoproteins and their downstream signaling networ...

Full description

Bibliographic Details
Main Authors: Cheng-Fen Tu, Fu-An Li, Ling-Hui Li, Ruey-Bing Yang
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Breast Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13058-022-01513-3