The Therapeutic Effects of Dodecaborate Containing Boronophenylalanine for Boron Neutron Capture Therapy in a Rat Brain Tumor Model

The Therapeutic Effects of Dodecaborate Containing Boronophenylalanine for Boron Neutron Capture Therapy in a Rat Brain Tumor Model

Background: The development of effective boron compounds is a major area of research in the study of boron neutron capture therapy (BNCT). We created a novel boron compound, boronophenylalanine–amide alkyl dodecaborate (BADB), for application in BNCT and focused on elucidating how it affected a rat...

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Bibliographic Details
Main Authors: Yusuke Fukuo, Yoshihide Hattori, Shinji Kawabata, Hideki Kashiwagi, Takuya Kanemitsu, Koji Takeuchi, Gen Futamura, Ryo Hiramatsu, Tsubasa Watanabe, Naonori Hu, Takushi Takata, Hiroki Tanaka, Minoru Suzuki, Shin-Ichi Miyatake, Mitsunori Kirihata, Masahiko Wanibuchi
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Biology
Subjects:
boron neutron capture therapy (BNCT)
malignant glioma
survival prolongation
boronophenylalanine–amide alkyl dodecaborate (BADB)
Online Access:https://www.mdpi.com/2079-7737/9/12/437

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https://www.mdpi.com/2079-7737/9/12/437

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