Systematic analysis of integrated bioinformatics to identify upregulated THBS2 expression in colorectal cancer cells inhibiting tumour immunity through the HIF1A/Lactic Acid/GPR132 pathway

Abstract Background THBS2, a member of the extracellular matrix glycoprotein family, can effectively inhibit tumour growth and angiogenesis. This study aimed to investigate the biological role of THBS2 in various types of cancers and the mechanisms underlying the malignant progression of colorectal...

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Bibliographic Details
Main Authors: Ye Liu, Chunhui Jiang, Chunjie Xu, Lei Gu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-023-03103-5