Three polymethoxyflavones from the peel of Citrus reticulata “Chachi” inhibits oxidized low-density lipoprotein-induced macrophage-derived foam cell formation

Three polymethoxyflavones from the peel of Citrus reticulata “Chachi” inhibits oxidized low-density lipoprotein-induced macrophage-derived foam cell formation

Foam cell formation is the hallmark of the development and progression of atherosclerosis. The aim of this study was to investigate the regulatory effects of three polymethoxyflavones (PMFs), namely, tangeretin (TAN), 5,6,7,3′,4′,5′-hexamethoxyflavone (HxMF), and 3,5,6,7,8,3′,4′-heptamethoxyflavone...

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Bibliographic Details
Main Authors: Pu-Lin Liang, Qian-Wen Liang, Pei-Wen He, Xue-Lian Chen, Ya Xu, Hai-Sheng Tu, Liang Zhang, Xiao-Hui Qiu, Jing Zhang, Zhi-Hai Huang, Wen Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
atherosclerosis
polymethoxyflavones
foam cells
inflammation
lipid metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.924551/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2022.924551/full

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