Proton-Dependent Gating and Proton Uptake by Wzx Support O-Antigen-Subunit Antiport Across the Bacterial Inner Membrane

ABSTRACT Wzx flippases are crucial for bacterial cell surface polysaccharide assembly as they transport undecaprenyl pyrophosphate-linked sugar repeat units from the cytoplasmic to the periplasmic leaflets of the inner membrane (IM) for final assembly. Our recently reported three-dimensional (3D) mo...

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Bibliographic Details
Main Authors: Salim T. Islam, Paul D. W. Eckford, Michelle L. Jones, Timothy Nugent, Christine E. Bear, Christian Vogel, Joseph S. Lam
Format: Article
Language:English
Published: American Society for Microbiology 2013-11-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00678-13