Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase.

Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase.

Increased pain sensitivity is a comorbidity associated with many clinical diseases, though the underlying causes are poorly understood. Recently, chronic pain hypersensitivity in rodents treated to induce chronic inflammation in peripheral tissues was linked to enhanced tryptophan catabolism in brai...

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Bibliographic Details
Main Authors: Lei Huang, Rong Ou, Guilherme Rabelo de Souza, Thiago M Cunha, Henrique Lemos, Eslam Mohamed, Lingqian Li, Gabriela Pacholczyk, Janice Randall, David H Munn, Andrew L Mellor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4863962?pdf=render

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http://europepmc.org/articles/PMC4863962?pdf=render

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