Red nucleus IL-33 facilitates the early development of mononeuropathic pain in male rats by inducing TNF-α through activating ERK, p38 MAPK, and JAK2/STAT3

Red nucleus IL-33 facilitates the early development of mononeuropathic pain in male rats by inducing TNF-α through activating ERK, p38 MAPK, and JAK2/STAT3

Abstract Background Our recent studies have identified that the red nucleus (RN) dual-directionally modulates the development and maintenance of mononeuropathic pain through secreting proinflammatory and anti-inflammatory cytokines. Here, we further explored the action of red nucleus IL-33 in the ea...

Full description

Bibliographic Details
Main Authors: Hao-Nan Li, Qing-Qing Yang, Wen-Tao Wang, Xue Tian, Fan Feng, Shu-Ting Zhang, Yu-Tong Xia, Jia-Xue Wang, Yuan-Wu Zou, Jun-Yang Wang, Xiao-Yan Zeng
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Journal of Neuroinflammation
Subjects:
Interleukin-33
Mononeuropathic pain
Red nucleus
Signaling pathway
Tumor necrosis factor-α
Online Access:https://doi.org/10.1186/s12974-021-02198-9

Internet

https://doi.org/10.1186/s12974-021-02198-9

Similar Items