Differential expression and analysis of extrachromosomal circular DNAs as serum biomarkers in pulmonary arterial hypertension

Differential expression and analysis of extrachromosomal circular DNAs as serum biomarkers in pulmonary arterial hypertension

Abstract Background Extrachromosomal circular DNAs (eccDNAs) have been reported to play a key role in the occurrence and development of various diseases. However, the characterization and role of eccDNAs in pulmonary arterial hypertension (PAH) remain unclear. Methods In the discovery cohort, we fir...

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Bibliographic Details
Main Authors: Chun Zhang, Qiang Du, Xiao Zhou, Tianyu Qu, Yingying Liu, Kai Ma, Ziling Shen, Qun Wang, Zaikui Zhang, Ruifeng Zhang
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Respiratory Research
Subjects:
EccDNA
Pulmonary arterial hypertension
High-throughput sequencing
Differential expression
Biomarker
Online Access:https://doi.org/10.1186/s12931-024-02808-z

Internet

https://doi.org/10.1186/s12931-024-02808-z

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