Clonal analysis of the T-cell response to in vivo expressed Mycobacterium tuberculosis protein Rv2034, using a CD154 expression based T-cell cloning method.

Clonal analysis of the T-cell response to in vivo expressed Mycobacterium tuberculosis protein Rv2034, using a CD154 expression based T-cell cloning method.

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of death worldwide. A better understanding of the role of CD4+ and CD8+ T cells, which are both important to TB protection, is essential to unravel the mechanisms of protection and to identify the key antigens see...

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Bibliographic Details
Main Authors: Susanna Commandeur, Mariateresa Coppola, Karin Dijkman, Annemieke H Friggen, Krista E van Meijgaarden, Susan J F van den Eeden, Louis Wilson, Jolien J van der Ploeg-van Schip, Kees L M C Franken, Annemieke Geluk, Tom H M Ottenhoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4048274?pdf=render

Internet

http://europepmc.org/articles/PMC4048274?pdf=render

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