RAB7A Regulates Vimentin Phosphorylation through AKT and PAK

RAB7A Regulates Vimentin Phosphorylation through AKT and PAK

RAB7A is a small GTPase that controls the late endocytic pathway but also cell migration through RAC1 (Ras-related C3 botulinum toxin substrate 1) and vimentin. In fact, RAB7A regulates vimentin phosphorylation at different sites and vimentin assembly, and, in this study, we identified vimentin doma...

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Bibliographic Details
Main Authors: Roberta Romano, Matteo Calcagnile, Azzurra Margiotta, Lorenzo Franci, Mario Chiariello, Pietro Alifano, Cecilia Bucci
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
cell migration
intermediate filaments
RAC1
beta-catenin
NF-kB
cofilin
Online Access:https://www.mdpi.com/2072-6694/13/9/2220

Internet

https://www.mdpi.com/2072-6694/13/9/2220

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