Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury

Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury

Neuropathic pain following peripheral nerve injury is associated with hyperexcitability in damaged myelinated sensory axons, which begins to normalise over time. We investigated the composition and distribution of shaker-type-potassium channels (Kv1 channels) within the nodal complex of myelinated a...

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Bibliographic Details
Main Authors: Margarita Calvo, Natalie Richards, Annina B Schmid, Alejandro Barroso, Lan Zhu, Dinka Ivulic, Ning Zhu, Philipp Anwandter, Manzoor A Bhat, Felipe A Court, Stephen B McMahon, David LH Bennett
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-04-01
Series:eLife
Subjects:
neuropathic pain
neuropathy
shaker type potassium channels
juxtaparanode
hypersensitivity
Online Access:https://elifesciences.org/articles/12661

Internet

https://elifesciences.org/articles/12661

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