Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury

Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury

Neuropathic pain following peripheral nerve injury is associated with hyperexcitability in damaged myelinated sensory axons, which begins to normalise over time. We investigated the composition and distribution of shaker-type-potassium channels (Kv1 channels) within the nodal complex of myelinated a...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Margarita Calvo, Natalie Richards, Annina B Schmid, Alejandro Barroso, Lan Zhu, Dinka Ivulic, Ning Zhu, Philipp Anwandter, Manzoor A Bhat, Felipe A Court, Stephen B McMahon, David LH Bennett
Format:	Artikel
Sprache:	English
Veröffentlicht:	eLife Sciences Publications Ltd 2016-04-01
Schriftenreihe:	eLife
Schlagworte:	neuropathic pain neuropathy shaker type potassium channels juxtaparanode hypersensitivity
Online Zugang:	https://elifesciences.org/articles/12661

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