Antidepressant effects of 70% ethanolic extract of Lonicerae japonicae flos and it contained chlorogenic acid via upregulation of BDNF-TrkB pathway in the hippocampus of mice

Antidepressant effects of 70% ethanolic extract of Lonicerae japonicae flos and it contained chlorogenic acid via upregulation of BDNF-TrkB pathway in the hippocampus of mice

Lonicera japonica flos (LJF) is a common clinical herb with outstanding medicinal and nutritional value. This study aimed to evaluate the antidepressant effects of LJF’s active extract and compound chlorogenic acid (CGA) around brain-derived neurotrophic factor(BDNF)-tropomyosin receptor kinase B (T...

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Bibliographic Details
Main Authors: Lingyu Qin, Junming Wang, Xiaohui Wu, Lingling Song, Yueyue Zhang, Mingzhu Gong, Yanmei Wang, Bingyin Li
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Brain Research Bulletin
Subjects:
Ethanolic extract of Lonicerae japonicae flos
The antidepressant active extract
Chlorogenic acid
The key antidepressant active compound
BDNF-TrkB pathway
Neurological nutrition
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923023002216

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http://www.sciencedirect.com/science/article/pii/S0361923023002216

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