Aerobic glycolysis enhances HBx-initiated hepatocellular carcinogenesis via NF-κBp65/HK2 signalling

Aerobic glycolysis enhances HBx-initiated hepatocellular carcinogenesis via NF-κBp65/HK2 signalling

Abstract Background Aerobic glycolysis has been recognized as one of the growth-promoting metabolic alterations of cancer cells. Emerging evidence indicates that nuclear factor κB (NF-κB) plays significant roles in metabolic adaptation in normal cells and cancer cells. However, whether and how NF-κB...

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Bibliographic Details
Main Authors: Lingjun Chen, Xianyi Lin, Yiming Lei, Xuan Xu, Qi Zhou, Yan Chen, Huiling Liu, Jie Jiang, Yidong Yang, Fengping Zheng, Bin Wu
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Hepatocellular carcinoma
Hepatitis B virus X protein
NF-κBp65
Aerobic glycolysis
Hexokinase 2
Online Access:https://doi.org/10.1186/s13046-022-02531-x

Internet

https://doi.org/10.1186/s13046-022-02531-x

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