Transcription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses

Transcription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses

Chronic ACTH exposure is associated with adrenal hypertrophy and steroidogenesis. The underlying molecular processes in mice have been analysed by microarray, histological and immunohistochemical techniques. Synacthen infused for 2 weeks markedly increased adrenal mass and plasma corticosterone leve...

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Bibliographic Details
Main Authors: Robert I Menzies, Xin Zhao, Linda J Mullins, John J Mullins, Carolynn Cairns, Nicola Wrobel, Donald R Dunbar, Matthew A Bailey, Christopher J Kenyon
Format: Article
Language:English
Published: Bioscientifica 2017-09-01
Series:Endocrine Connections
Subjects:
ACTH
cholesterol
adrenal hyperplasia
adrenal hypertrophy
Online Access:http://www.endocrineconnections.com/content/6/7/446.full

Internet

http://www.endocrineconnections.com/content/6/7/446.full

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