Periostin facilitates ovarian cancer recurrence by enhancing cancer stemness

Abstract The lethality of epithelial ovarian cancer (OC) is largely due to a high rate of recurrence and development of chemoresistance, which requires synergy between cancer cells and the tumor microenvironment (TME) and is thought to involve cancer stem cells. Our analysis of gene expression micro...

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Bibliographic Details
Main Authors: Zhiqing Huang, Olivia Byrd, Sarah Tan, Katrina Hu, Bailey Knight, Gaomong Lo, Lila Taylor, Yuan Wu, Andrew Berchuck, Susan K. Murphy
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48485-8