A deep generative model for multi-view profiling of single-cell RNA-seq and ATAC-seq data

A deep generative model for multi-view profiling of single-cell RNA-seq and ATAC-seq data

Abstract Here, we present a multi-modal deep generative model, the single-cell Multi-View Profiler (scMVP), which is designed for handling sequencing data that simultaneously measure gene expression and chromatin accessibility in the same cell, including SNARE-seq, sci-CAR, Paired-seq, SHARE-seq, an...

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Bibliographic Details
Main Authors: Gaoyang Li, Shaliu Fu, Shuguang Wang, Chenyu Zhu, Bin Duan, Chen Tang, Xiaohan Chen, Guohui Chuai, Ping Wang, Qi Liu
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-021-02595-6

Internet

https://doi.org/10.1186/s13059-021-02595-6

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