Rat mesenchymal stromal cells inhibit T cell proliferation but not cytokine production through inducible nitric oxide synthase

Mesenchymal stromal cells (MSC) have important immunomodulatory properties, they inhibit T lymphocyte allo-activation and have been used to treat graft-versus-host disease. How MSC regulate immunosuppressive functions is not completely understood but species-dependent mechanisms have been indicated....

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Bibliographic Details
Main Authors: Severin eZinöcker, John T. eVaage
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00062/full