Development and Validation of a Novel HPLC Method for the Determination of Ephedrine Hydrochloride in Nasal Ointment

Development and Validation of a Novel HPLC Method for the Determination of Ephedrine Hydrochloride in Nasal Ointment

A simple, precise, and cost-effective reverse phase ion pair chromatographic (RP-IP-HPLC) method was developed and validated for the determination of Ephedrine Hydrochloride in a nasal ointment. A simple and fast extraction protocol was developed for the effective recovery of the analyte, and for th...

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Bibliographic Details
Main Authors: Konstantinos Kallinteris, Kostas Gkountanas, Iοannis Karamitros, Haris Boutsikaris, Yannis Dotsikas
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Separations
Subjects:
ephedrine
nasal ointment
extraction
ion pair chromatography
robustness testing
experimental design
Online Access:https://www.mdpi.com/2297-8739/9/8/198

Internet

https://www.mdpi.com/2297-8739/9/8/198

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