Flavonoids Regulate Redox-Responsive Transcription Factors in Glioblastoma and Microglia

Flavonoids Regulate Redox-Responsive Transcription Factors in Glioblastoma and Microglia

The tumor microenvironment (TME) has emerged as a valuable therapeutic target in glioblastoma (GBM), as it promotes tumorigenesis via an increased production of reactive oxygen species (ROS). Immune cells such as microglia accumulate near the tumor and its hypoxic core, fostering tumor proliferation...

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Bibliographic Details
Main Authors: Natali Joma, Issan Zhang, Germanna L. Righetto, Laura McKay, Evan Rizzel Gran, Ashok Kakkar, Dusica Maysinger
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cells
Subjects:
microglia
glioblastoma
tumor microenvironment
reactive oxygen species
oxidative stress
natural polyphenols
Online Access:https://www.mdpi.com/2073-4409/12/24/2821

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https://www.mdpi.com/2073-4409/12/24/2821

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