What contributes to an effective mannose recognition domain?

In general, carbohydrate–lectin interactions are characterized by high specificity but also low affinity. The main reason for the low affinities are desolvation costs, due to the numerous hydroxy groups present on the ligand, together with the typically polar surface of the binding sites. Nonetheles...

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Bibliographic Details
Main Authors: Christoph P. Sager, Deniz Eriş, Martin Smieško, Rachel Hevey, Beat Ernst
Format: Article
Language:English
Published: Beilstein-Institut 2017-12-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.13.255