Precision genetic cellular models identify therapies protective against ER stress

Precision genetic cellular models identify therapies protective against ER stress

Abstract Rare monogenic disorders often share molecular etiologies involved in the pathogenesis of common diseases. Congenital disorders of glycosylation (CDG) and deglycosylation (CDDG) are rare pediatric disorders with symptoms that range from mild to life threatening. A biological mechanism share...

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Bibliographic Details
Main Authors: Irina V. Lebedeva, Michelle V. Wagner, Sunil Sahdeo, Yi-Fan Lu, Anuli Anyanwu-Ofili, Matthew B. Harms, Jehangir S. Wadia, Gunaretnam Rajagopal, Michael J. Boland, David B. Goldstein
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04045-4

Internet

https://doi.org/10.1038/s41419-021-04045-4

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