The effects of bacterial endotoxin LPS on synaptic transmission at the neuromuscular junction

The direct action of bacterial lipopolysaccharides (LPS) endotoxin was shown to enhance synaptic transmission and hyperpolarize the membrane potential at low doses, but block glutamatergic receptors and decrease observable spontaneous events at a high dosage. The dosage effects are LPS type specific...

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Bibliographic Details
Main Authors: Robin L. Cooper, Micaiah McNabb, Jeremy Nadolski
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S240584401836105X