Caffeine and Cisplatin Effectively Targets the Metabolism of a Triple-Negative Breast Cancer Cell Line Assessed via Phasor-FLIM

Caffeine and Cisplatin Effectively Targets the Metabolism of a Triple-Negative Breast Cancer Cell Line Assessed via Phasor-FLIM

Triple-negative tumor cells, a malignant subtype of breast cancer, lack a biologically targeted therapy. Given its DNA repair inhibiting properties, caffeine has been shown to enhance the effectiveness of specific tumor chemotherapies. In this work, we have investigated the effects of caffeine, cisp...

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Bibliographic Details
Main Authors: Stephanie M. Pascua, Gabrielle E. McGahey, Ning Ma, Justin J. Wang, Michelle A. Digman
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
caffeine
cisplatin
phasor-FLIM
energy metabolism
breast cancer
Online Access:https://www.mdpi.com/1422-0067/21/7/2443

Internet

https://www.mdpi.com/1422-0067/21/7/2443

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