Drug–target interaction prediction using unifying of graph regularized nuclear norm with bilinear factorization
Abstract Background Wet-lab experiments for identification of interactions between drugs and target proteins are time-consuming, costly and labor-intensive. The use of computational prediction of drug–target interactions (DTIs), which is one of the significant points in drug discovery, has been cons...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-11-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-021-04464-2 |