99mTc-labeled iRGD for single-positron emission computed tomography imaging of triple-negative breast cancer

99mTc-labeled iRGD for single-positron emission computed tomography imaging of triple-negative breast cancer

Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype, with a high mortality rate. One of the main reasons for this poor prognosis is the failure of a specific diagnosis. As a tumor-homing and penetrating peptide, iRGD has not only the properties of binding to neuropilin-...

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Bibliographic Details
Main Authors: Buhui Yu, Hongxing Su, Lingzhou Zhao, Jiqin Yang, Meilin Zhu, Jinhua Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
triple-negative breast cancer
iRGD
neuropilin-1
integrin αvβ3
SPECT imaging
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.1001899/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.1001899/full

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